Antioxidant activity of two isomeric benzoxepin derivatives from the stem bark of Bauhinia Aculeata L.

Tanjung, Mulyadi and Ratih Dewi Saputri, Ratih Dewi and Tjahjandarie, Tjitjik Sri (2014) Antioxidant activity of two isomeric benzoxepin derivatives from the stem bark of Bauhinia Aculeata L. Journal of Chemical and Pharmaceutical Research, 6 (1). pp. 705-708. ISSN 0975-7384

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Abstract

Two benzooxepin types isolated from the stem bark of Bauhinia aculeata L. (Fabaceae) have been identified as bauhiniastin 4 (1) and pacharin (2). The structure of both compounds have been elucidated based on its spectroscopic data, including UV, 1D and 2D NMR, and HREISMS spectra. Compounds 1 – 2 were evaluated for their radical scavenging against 2,2-diphenyl-1-picrylhydrazyl (DPPH), showing their IC50 were 32.7, and 1495.2 µM, respectively. The results indicate that as bauhiniastin 4 (1) slightly more active than ascorbic acid (62.8 µM).

Item Type: Article
Uncontrolled Keywords: Benzooxepin, Bauhinia aculeata L., Elucidation structure, Antioxidant
Subjects: Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Tanjung, MulyadiUNSPECIFIED
Ratih Dewi Saputri, Ratih DewiUNSPECIFIED
Tjahjandarie, Tjitjik SriUNSPECIFIED
Depositing User: Mr Akhmad Nurfizal Reza
Date Deposited: 12 Oct 2017 20:24
Last Modified: 12 Oct 2017 20:24
URI: http://repository.unair.ac.id/id/eprint/63034
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