Tjahjandarie, Tjitjik Srie and Saputri, Ratih Dewi and Tanjung, Mulyadi (2015) Synthesis pterocarpan compounds from Erythrina crista-galli L and their action towards Plasmodium falciparum. Journal of Chemical and Pharmaceutical Research, 7 (1). pp. 666-670. ISSN 0975-7384
|
Text
Cover.pdf Download (17kB) | Preview |
|
|
Text
Bukti C10. Synthesis pterocarpan compounds from Erythrina ..........pdf Download (3MB) | Preview |
|
|
Text
Bukti C10 Peer reviewer dan validasi Kadep.pdf Download (1MB) | Preview |
Abstract
Synthesis of the naturally occurred 3-acetyl sandwicensin(2) and 2,7- dibromosandwicensin(3)was carried out by acetylation and bromination reaction, respectively. The pterocarpan synthesized in this study was andwicensin(1) isolated from stem bark of Erythrina crista galli L. Their structures were established on the basis of spectroscopic evidence. Compounds 1–3 were evaluated for their antimalarial properties against Plasmodium palcifarum, showing their IC were 1.83, 34.81 and 12.9 µg/mL, respectively.
| Item Type: | Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Uncontrolled Keywords: | 3-acetyl sandwicensin, 2,7-dibromosandwicensin, acetylation reaction, bromination reaction, antimalarial activity. | ||||||||
| Subjects: | Q Science > QD Chemistry | ||||||||
| Divisions: | 08. Fakultas Sains dan Teknologi > Kimia | ||||||||
| Creators: |
|
||||||||
| Depositing User: | Mr Akhmad Nurfizal Reza | ||||||||
| Date Deposited: | 12 Oct 2017 23:26 | ||||||||
| Last Modified: | 12 Oct 2017 23:26 | ||||||||
| URI: | http://repository.unair.ac.id/id/eprint/63040 | ||||||||
| Sosial Share: | |||||||||
Actions (login required)
 |
View Item |