CYNTIA DEWI RETNO INDRIANI, 061311133030 (2017) EFEKTIVITAS GEL EKSTRAK DAUN BINAHONG (Anredera cordifolia ( Ten.) Steenis) TERHADAP LUKA BAKAR PADA MENCIT (Mus musculus) MELALUI PENGAMATAN INFLAMASI. Skripsi thesis, Universitas Airlangga.

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Abstract

Wound healing is a normal process as response to skin tissue injury. This research conducted to see the effect of binahong leaves gel extract for healing burn on mice. Divided into 4 groups, namely P0 negative control group, positive control group administered Bioplasenton P1, P2 group administered binahong leaves gel extract 10%, P3 administered binahong leaves gel extract 20%. By making a burn on the right side of the mice’s back with a wound diameter of 2 cm. Gel applied to the treatment group twice daily for 7 days. Measurements were made on days 3, 5 and 7 by using a sliding range. Data were analyzed by Kruscall-Wallis test and continued by Mann-Whitney test. The results showed that the binahong leaves gel extract was able to heal burns on the administration of Bioplasenton and 20% concentrated gel, the burn diameter decreased and inflammation process occured at day 7, then the higher concentration of extracts gave more healing effect on burns (p<0,05).

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