Firsta Wahono Febrianto, NIM011411131022 (2017) HUBUNGAN PENURUNAN KADAR CD4 DENGAN POLA KEPEKAAN MYCOBACTERIUM TUBERCULOSIS TERHADAP RIFAMPISIN PADA PASIEN KO-INFEKSI TB-HIV DI RSUD DR. SOETOMO SURABAYA. Skripsi thesis, Universitas Airlangga.
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Abstract
Background: Rifampicin-resistance Tuberculosis (TB) case rate is increasing every year, particularly in Indonesia. It is probably caused by the infection of Human Immunodeficiency Virus (HIV) on Tuberculosis patient, called TB-HIV co-infection. However, the association between HIV infection, which can cause decreasing of CD4, and Rifampicin-resistance Mycobacterium tuberculosis in TB-HIV co-infection patients is still not clearly yet. Objective: This study was undertaken to describe the demographics profile of TB-HIV co-infection patients and analyze the association between CD4 decreasing and Rifampicin resistance in TB-HIV co-infection patients of Dr. Soetomo General Hospital Surabaya. Methods: A retrospective research with cross-sectional method of TB-HIV co-infection patients’ medical record at Medical Record Center of Dr. Soetomo General Hospital Surabaya from 1 January to 31 December 2016 with 40 samples. Result: TB-HIV co-infection was common in male (70%). It was dominated by the productive age between 25-44 years old (55%). Most of them were high school graduated (80%) and 52,5% of them had been married. Rifampicin-sensitive Mycobacterium tuberculosis was still the most found (86%). Chi Square test shows that there is no association (p=0,545) between CD4 decreasing and Rifampicin-resistance Mycobacterium tuberculosis in TB-HIV co-infection patients of Dr. Soetomo General Hospital Surabaya. Conclusion: TB-HIV co-infection was common in male, productive age, high school graduated, and married patients. Rifampicin-sensitive Mycobacterium tuberculosis was still the most found and there is no association between CD4 decreasing and Rifampicin-resistance Mycobacterium tuberculosis in TB-HIV co-infection patients.
| Item Type: | Thesis (Skripsi) | |||||||||
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| Additional Information: | KKA KK FK.PD.357/17 Feb h | |||||||||
| Uncontrolled Keywords: | Clinical profile, TB-HIV co-infection, Mycobacterium tuberculosis, Rifampicin resistance, CD4. | |||||||||
| Subjects: | R Medicine > RC Internal medicine > RC306-320.5 Tuberculosis | |||||||||
| Divisions: | 01. Fakultas Kedokteran | |||||||||
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| Depositing User: | Mr Binkol2 2 | |||||||||
| Date Deposited: | 19 Feb 2018 17:05 | |||||||||
| Last Modified: | 19 Feb 2018 17:05 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/68446 | |||||||||
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