Nur Khamidah (2018) PERBANDINGAN KOLONISASI Staphylococcus aureus PASIEN DERMATITIS ATOPIK NON-EKSASERBASI PADA ANAK DAN KONTROL. Thesis thesis, Universitas Airlangga.

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Abstract

Background: Atopic dermatitis is a chronic pruritik inflammatory skin disease, typically affect children then adult. Defective skin barrier, defect innate immune system, and heightened immunologic responses allow increased colonization by various organisms even in normal skin of atopic dermatitis patient. Staphylococcus aureus, the most virulence species from Staphylococcus genus, is one of bacteria that have a big role in atopic dermatitis. Purpose: To compared colony of Staphylococcus aureus from antecubital non-exacerbate child with atopic dermatitis than normal child without history of atopic dermatitis. Method: Antecubital skin swabs for culture collected from 17 patients with non-exacerbated atopic dermatitis and 17 controls to investigate the presence of Staphylococcus aureus colonization and count the number of colonies. Result: Staphylococcus aureus skin colonization was seen in 5 patients (29,41%) but none in control group (p=0.044), relative risk 2.417. All of positive colonization revealed moderate and heavy bacterial growth (104->105 cfu/cm2) Conclusions: Non-exacerbated atopic dermatitis child patients showed increased risk of Staphylococcus aureus colonization than normal child.

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