PENGARUH KONSENTRASI POLIMER ALGINAT TERHADAP AKTIVITAS IN VITRO MIKROSFER SIPROFLOKSASIN HCl – ALGINAT PADA Staphylococcus aureus DAN Pseudomonas aeruginosa

HUSNIATUL FITRIAH, 051411131016 (2018) PENGARUH KONSENTRASI POLIMER ALGINAT TERHADAP AKTIVITAS IN VITRO MIKROSFER SIPROFLOKSASIN HCl – ALGINAT PADA Staphylococcus aureus DAN Pseudomonas aeruginosa. Skripsi thesis, Universitas Airlangga.

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Abstract

The aim of this research was to investigate antibacterial activity of microsphere ciprofloxacin HCl using alginate as polymer matrix. Antibacterial test was performed by diffusion method using bacteria Staphycloccus aureus and Pseudomonas aeruginosa. Antibacterial activity of microsphere ciprofloxacin HCl microspheres in phospat buffer solution pH 7,2 ± 0,1 as stimulated of pH condition of cystic fibrosis’s patient. Fresh ciprofloxacin HCl – alginate microspheres and ciprofloxacin HCl release samples at interval time of 0, 8, 12, 16, and 24 hours. Result showed an equal between standart ciprofloxacin HCl standart, microsphere siprofloksasin HCl and microsphere ciprofloxacin HCl with release samples from microsphere on treatment of Staphycloccus aureus and Pseudomonas aeruginosa bacteria.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.F. 51-18 Fit p
Uncontrolled Keywords: Ciprofloxacin HCl, Microsphere, Antibacterial Activity.
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsNIM
HUSNIATUL FITRIAH, 051411131016UNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorDewi Melani Hariyadi, S.Si., M.Phil., Ph.D., AptUNSPECIFIED
Thesis advisorEsti Hendradi, Dra., M.Si., Ph.D., Apt.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 28 Dec 2018 05:06
Last Modified: 28 Dec 2018 05:06
URI: http://repository.unair.ac.id/id/eprint/77314
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