Maftuchah Rochmanti, dr. and Sri Agus Sudjarwo, Ph.D., drh. (2006) POTENSI ANTI ALERGI EKSTRAK BAWANG PUTIH DALAM MENURUNKAN KADAR IMUNOLOBULIN E PADA MENCIT YANG DIUNDUKSI OVALBUMIN. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

We investigated the potency of garlic extract on immunoglobuline E production in mice. The garlic extract was orally administered to mice before injected intraperitoncally with ovalbumin, and the level of IgE in serum was determined. The mice were divided into the control groups were saline perorally, garlic exctract groups received doses of 100; 200 and 400 mg/kg garlic exctract (peroral) respectively. This was followed by the administration ovalbumin at dose 1 ug/g BW through the intraperitoneal route 60 min after administration garlic extract or saline. Results indicated that the increase in immunoglobuline E production after ovalbumin injection was significantly prevented by preadministration of the garlic exctract at 400 mg/kg BW but not garlic exctract at 100 and 200 mg/kg BW. These resultas suggest that garlic exctract at dose 400 mg/kg BW has antiallergy properties.

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