Dwikora Novembri Utomo and Ferdiansyah Mahyudin and Kukuh D. Hernugrahanto and Heri Suroto and Muhammad Zaim Chilmi and Fedik Abdul Rantam (2018) Implantation of platelet rich fibrin and allogenic mesenchymal stem cells facilitate the healing of muscle injury: An experimental study on animal. International Journal of Surgery Open, 11. pp. 4-9. ISSN 2405-8572

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Abstract

Muscle injury has caused adverse impacts on athletes' performance. Muscle injury treatments are based on the degree of severity. Unfortunately, in extensive injuries, surgical treatments are often unsatisfactory especially in athletes with high functional demand. More effort is needed to achieve a better result in muscle injury healing. The use of platelet-rich fibrin (PRF) and mesenchymal stem cell (MSC) would provide all the necessary factors to achieve good tissue healing: cells, growth factors, and scaffold. The study aims to evaluate the role of PRF and MSC in facilitating the healing of muscle injury on animal models.

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