Noorma Rosita and Tristiana Erawati and Rafi Jikrona (2009) The Influence of Arbutin 3% and Sesame Oil (3,5,7 % w/w) on SPF Values of Oxybenzon and Padimate O (3,7 % w/w) in Carbomer Gel Base. In: Proceeding The 1st International Conference on Pharmacy and Advanced Pharmaceutical Sciences. Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, pp. 38-43. ISBN 978-979-95107-7-8

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Abstract

This research was intended to know the influence of addition 3% Arbutin and (3;5;7)% w/w sesame oil on SPF value of sunscreen combination Oxybenzone and Padimate - O (3:7 % w/w) was formulated in carbomer gel base. Characteristic test was done in 2nd day after formulated included organoleptic, pH, and spread-ability. The sunscreen effectiveness determination (SPF value) was performed in vitro by measuring the absorbencies of its 10 ppm solutions in isopropanol between 290 - 400 nm. Organoleptic characteristic all formulas were different with the base, so did the pH and spread ability result. From SPF value determination results conclude that addition of arbutin increased SPF value, so did the increased of sesame oil concentration. Formula with the higher concentration of sesame oil had a higher SPF values. From this research, there was suggested to evaluate in vivo acceptability test and affectivity in vivo trial test on human skin.

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