Windy Ayustyas Trisna, NIM011411131034 (2019) KORELASI STATUS HORMONAL ESTROGEN RESEPTOR DENGAN DERAJAT KEGANASAN KANKER PAYUDARA JENIS DUKTAL INVASIF DI RSUD DR. SOETOMO TAHUN 2015-2017. Skripsi thesis, Universitas Airlangga.

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Abstract

Globocan data, shows the incidence of cancer in Indonesia at 136.2 per 100,000 population. The highest case in female is breast cancer at 42.1 per 100,000 population. The most common type of breast cancer is invasive ductal type. The life possibility of patients with a high degree of malignancy (Grade III) is only 11.86% while for patients with a low degree of malignancy (Grade I) can reach 71.69%. Exposure to estrogen is a risk factor for breast cancer. This hormone show its effects through estrogen receptor which is a core protein. Patients with positive receptor have a better 5 to 10 years survival rate than patients with negative estrogen receptor, because patients who have this receptor will respond to hormonal therapy. Aim: Identifies the correlation between receptor estrogen hormonal status and invasive ductal type of breast cancer malignancy.

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