Abdul Rohim Tualeka, NIDN. 0024116603 and Tri Martiana, NIDN. 0003035607 and Ananto Dwi Wibrata and Pudji Rahmawati (2019) Effect of Food Consumption Contain Glutahione Anti-oxidant towards LDL Cholesterol Concentrations on Benzene-exposed-workers at the Romokalisari Shoe Industry, Surabaya. Indian Journal of Forensic Medicine and Toxicology, 13 (4). pp. 453-457. ISSN 0973-9122

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Abstract

Background: Benzene is a chemical that is often used in the shoe making industry. Recent studies have shown that benzene can cause a risk of cardiovascular disease by increasing LDL levels in blooda. One efficient intervention is consumption antioxidant-rich foods regularly to reduce blood LDL levels. Research on the effect of LDL cholesterol levels before and after treatment of consumption in benzene-exposed workers is still limited in Indonesia. Methods and Material: A sample of 25 workers with the pre-post test design method. Benzene measurement using the method ofNIOSH 1501 with an activated carbon ( charcoal) pipe which uses a gaschromatography­ flame ionization detector (GC-FID) technique using standard NIOSH 1501. An LDL cholesterol sample is taken by taking blood from a vein in the elbow fold (fossa cubiti). The statistical analysis used was Pearson and Spearman test and Paired t-test. Result: The majority of respondents have male sex, aged over 50 years. having a high school education background, never wearing a mask while working and having a smoking habit. There is no a difference between the levels of LDL cholesterol in blood before and after consumption food rich in glutathione antioxidants (p = 0107) and there is no correlation between the levels of benzene before and after treatment (p = 0.425; p = 0597). Conclusion: There are patterns that vary between LDL cholesterol-rich antioxidants before and after treatment. This can be due to lack time of monitoring in the study, the majority of respondents who still have normal concentration standards and the presence of demographic factors that can influence, for example smoking habit so there is no difference between LDL cholesterol levels before and after treatment. However, workers are recommended to always use PPE, do routine health checks while do physical activity and consume antioxidant-rich foods especially glutahione to prevent cardiovascular risk due to exposure to long­ term benzene (more than 10 years).

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