Aktivitas Invitro Enzim Fibrinolitik Ekstrak Tempe Hasil Fermentasi Rhizopus Oligosporus ATCC 6010 Pada Substrat Kedelai Hitam

Achmad Toto Poernomo and Isnaeni and Purwanto (2015) Aktivitas Invitro Enzim Fibrinolitik Ekstrak Tempe Hasil Fermentasi Rhizopus Oligosporus ATCC 6010 Pada Substrat Kedelai Hitam. Berkala Ilmiah Kimia Farmasi, 4 (2). pp. 18-24. ISSN 2302-8270

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Abstract

Screening of fibrinolytic activity of tempeh extract derived from Rhizopus oligosporus ATCC 6010 fermentation has been investigated. The fermentation used Glycine Soja Sieb. et Zucc, Canavalia ensiformis, Phaseolus radiaus L., Lablab purpureus, Glysine max (L) Merrill, Glycine Soja Sieb. et Zucc, and Vigna unguiculata as substrates. Nattokinase and phosphate buffer 0,05 M pH 5,0 was used as positive and negative control respectively. The proteolytic and fibrinolytic activity of fermentation product used five kinds of legumes has been compared each other. The Glycine Soja Sieb. et Zucc exhibited the highest activity with proteolytic and fibrinolytic index of the crude enzyme is 3.00 ± 1.58 and 3,07 ± 0,15 respectively. Ratio of the proteolytic and fibrinolytic index between the crude enzyme and nattokinase is 112,36 % and 88,14% respectively.

Item Type: Article
Uncontrolled Keywords: Fibrinolytic, trombosis, tempeh extract, Rhizopus oligosporus ATCC 6010
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM
Achmad Toto PoernomoNIDN0018095905
IsnaeniNIDN0013015603
PurwantoUNSPECIFIED
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 13 Jan 2020 04:36
Last Modified: 13 Jan 2020 04:36
URI: http://repository.unair.ac.id/id/eprint/90580
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