PENGARUH KONSENTRASI POLIMER TERHADAP DRUG DEPOSITION MIKROSFER CIPROFLOXACIN HCl- KARAGENAN DI PARU TIKUS

CINDY ALICIA ESTHERLINE, 051511133139 (2019) PENGARUH KONSENTRASI POLIMER TERHADAP DRUG DEPOSITION MIKROSFER CIPROFLOXACIN HCl- KARAGENAN DI PARU TIKUS. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The aim of this research was to investigate drug deposition of ciprofloxacin HCl using carageenanmicrosphere as polymer matrix. Microspheres waere administered to rat using nose-only exposure method as rat is know as nose only-breathing animal. Drug deposition in rat lungs was observed using fluorescence microscope and Rhodamine B as fluorochrome. The result showed that the microspheres system was able to get ciprofloxacin to the target site and the increase in polymer concentration prolong the drug residence time in lung.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.F 30/19 Est p
Uncontrolled Keywords: Ciprofloxacin HCl,Carageenan, Microsphere, Drug Deposition.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsNIM
CINDY ALICIA ESTHERLINE, 051511133139UNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorDewi Melani Hariyadi, S.Si., M.Phil., Ph.D., Apt., NIDN: '0026027801UNSPECIFIED
Depositing User: Dwi Marina
Date Deposited: 11 Nov 2019 03:48
Last Modified: 11 Nov 2019 03:48
URI: http://repository.unair.ac.id/id/eprint/90660
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