Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L. Repository

Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L.

Mulyadi Tanjung and Ratih Dewi Saputri and Faiz Fakhriah Fitriati and Tjitjik Srie Tjahjandarie (2016) Antimalarial and Antioxidant Activities of Isoprenylated Coumarins from the Stem Bark of Mesua borneensis L. Journal of Biologically Active Products from Nature, 6 (2). pp. 95-100. ISSN 2231-1866

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Official URL: https://www.tandfonline.com/doi/abs/10.1080/223118...

Abstract

The aim of this study was to assess the antimalarial and antioxidant effects of the n-hexane and ethyl acetate extracts together with three isolated isoprenylated coumarins, mammea A/BA(1),mammea A/ AA cyclo D (2) and mesuol (3) from the stem bark of M. borneensis L. The n-hexane and ethyl acetate extracts, as well as compounds 1-3 were evaluated for their antimalarial activity against Plasmodium falciparum strain 3D7 (chloroquine-sensitive) and their antioxidant activity against DPPH radical scavenging. Compound 2 exhibited slightly more active than chloroquine. Compounds 1 and 3 showed very high activity against DPPH radical.

Item Type:

Article

Uncontrolled Keywords:

Isoprenylated coumarin, Mesua borneensis L., Antimalarial, Antioxidant.

Subjects:

Q Science > Q Science (General)
Q Science > QD Chemistry

Divisions:

08. Fakultas Sains dan Teknologi > Kimia

Creators: