Prenylated Dihydrostilbenes From Macaranga rubiginosa Repository

Prenylated Dihydrostilbenes From Macaranga rubiginosa

Mulyadi Tanjung and Euis H. Hakim and Yana M. Syah (2017) Prenylated Dihydrostilbenes From Macaranga rubiginosa. Chemistry of Natural Compunds, 53 (2). pp. 215-218. ISSN 0009-3130

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Official URL: https://link.springer.com/article/10.1007/s10600-0...

Abstract

Phytochemical isolation of the methanol extract of Macaranga rubiginosa leaves afforded five prenylated dihydrostilbenes. Two of them were known dihydrostilbenes laevifolins A (1) and B (2), while the other three were new compounds, trivially named macarubiginosins A–C (3–5). The structures of the new compounds were elucidated based on their UV, 1D and 2D NMR, and HR-ESI-MS spectral data. Compounds 1–5 were tested for their cytotoxicity against P-388 cells, showing that compound 1 was the most active with IC 50 4.3 µM.

Item Type:

Article

Uncontrolled Keywords:

Keywords: macarubiginosins A–C, laevifolins A and B, prenylated dihydrostilbenes, Macaranga rubiginosa, Euphorbiaceae, cytotoxicity, P-388 cells.

Subjects:

Q Science > Q Science (General)
Q Science > QD Chemistry

Divisions:

08. Fakultas Sains dan Teknologi > Kimia

Creators: