Tjitjik Srie Tjahjandarie and Ratih Dewi Saputri and Mulyadi Tanjung (2016) Phenolic Compounds from The Stem Bark Erythrina Orientalis and Detection of Antimalaria Activity by ELISA. In: 5th International Conference and Workshop on Basic and Applied Sciences (ICOWOBAS 2015). AIP Conference Proceedings (1718). AIP Publishing, New York, 060007-1. ISBN 978-0-7354-1364-1

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Abstract

Abstract. Erythrina orientalis has local name “Dadap”. This plant has known producing alkaloids, flavonoids, pterocarpans, stilbenes, and arylbenzofurans which are active compounds.Three prenylated flavonoids, 8prenyl-daidzein (1), alpinumisoflavone (2) and 4’-O-methyl licoflavanone (3) had been isolated from the stem bark of Erythrina Orientalis. The structures were elucidated on the basis of spectroscopic data,which ar IR, UV, MS, and NMR 1D ( 1 H-NMR and 13 C-NMR) and 2D (COSY, HMQC, and HMBC). Compounds 1-3 were evaluated for their antimalaria with ELISA methods, which showed percentage inhibitionvalues of74.46%, 62.06%, and 0% respectively. Based on the inhibition value showed 4’-O-methyl licoflavanone (1) exhibit very high antimalaria activity compared to compounds (2) and (3).

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