Herry Agoes Hermadi and Widjiati and Lucia Tri Suwanti and Mufasirin and Djoko Legowo (2017) Gambaran Histopatologi Serviks Mencit (Mus musculus) yang Diinfeksi Stadium Takizoit Toxoplasma gondii Intravagina. Journal of Parasite Science, 1 (1). pp. 11-14. ISSN 2599-0993

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Abstract

The aim of this research is to find out histopathology appearance of vagina that infected by tachyzoit stadium Toxoplasma gondii mice (Mus musculus) cervix. Experimental animal used eighteen female mice with age of 2-3 month were divided randomly into two group treatment (n=9). P0 was the control group treated NaCl fisiologis intravagina and P1 was infected Toxoplasma gondii mice in first group was giving NaCl for control group, and second group was infected by tachyzoites of Toxoplasma gondii 1x103 by intravagina. Eight days after this exposure, mice sacrificed and cervix of all mice were taken for histopathology preparations were made for further observation and scoring. Each of the cervix of mice (Mus musculus) processed by Hematoxylin Eosin staining method. This research showed that tachyzoites of Toxoplasma gondii could be find of the cervix epitel. Base on the result of the statistical analysis by Mann whitneytest showed that there were significantly different result of erotion cervix epitel and the inflammatory cell (p<0.05), hyperplasia cervix epitel are not significantly (p>0.05) with erotion cervix epitel. Key words: Toxoplasma gondii, tachyzoites, cervix histological, erotion epitel, inflamatory cell, hyperplasia

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