INTAN KRIS PRASETYANTI, 050710147 (2011) STANDARISASI DAN PENETAPAN PROFIL EKSTRAK ETANOL 96% PERIKARPIUM MANGGIS (Garcinia mangostana L.). Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
Mangosteen pericarps ( Garcinia mangostana L. ) had been used as traditional medicine. α -mangosteen, that content in Garciniae pericarpium, was known have cytotoxic activity so that extract of mangosteen pericarps ( Garcinia mangostana L. ) potential to developed as standardized herbal drug and phytopharmaca product. Therefore, in this research, general standard parameter and fingerprint of ethanol 96% extract of mangosteen pericarps was determined. Mangosteen pericarps which originated from Trenggalek, East Java, and then washed, cut, dried by oven in 50 o C and grinded into powders. Furthermore, the powders made into extract by maceration in 96% ethanol for 24 hours. Extract obtained to be condensed by evaporated in vacuo until got a viscous extract. Next, the general standard parameter and fingerprint was determined The result of the general standard parameter determination of ethanol 96% extract mangosteen pericarps ( Garcinia mangostana L. ) showed that value of loss on drying was (18,27 ± 0,02)%b/b, water content was (11,44 ± 0,2) %v/b, total ash content was (1,64 ± 0,04) %b/b, acid insoluble ash content was (1,189 ± 0,09), wáter soluble ash content was (1,46 ± 0,05) %b/b, Pb content was 0,201 mg/kg, Hg and As content was undetected, Cd content was 0,038 mg/kg, Cu content was 0,014 mg/kg, water soluble substances content was (14,48 ± 0,45) %b/b, ethanol soluble substances content was (80,46 ± 1,12) %b/b, and α -mangostin content was (21,65 ± 1,30) %b/b. Fingerprint determination of ethanol 96% extract showed that there are only two peaks in TLC-densitometer chromatogram. Obtained spectra from FTIR show that there are another function group in extract if compared with α - mangosteen standard.
| Item Type: | Thesis (Skripsi) | |||||||||
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| Additional Information: | KKB KK FF 298 11 Pra s | |||||||||
| Uncontrolled Keywords: | megakaryocytes ; medicinal plants ; cassia ( gennius) | |||||||||
| Subjects: | R Medicine > R Medicine (General) | |||||||||
| Divisions: | 05. Fakultas Farmasi > Farmakognosi Fitokimia | |||||||||
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| Depositing User: | Dwi Marina | |||||||||
| Date Deposited: | 26 Jan 2012 12:00 | |||||||||
| Last Modified: | 19 Jul 2016 10:59 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/9576 | |||||||||
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