GADHANG DEWANGGA, 050710093 (2011) PENGARUH GELATIN TERHADAP MUTU FISIK DANb DISOLUSI ORALLY DISINTEGRATING TABLET PIROKSIKAM DENGAN SUPERDISINTEGRAN CMC-Ca 7,5 % DAN BASIS MANITOL (Dibuat dengan Metode Freeze Drying). Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
Orally Disintegrating Tablets, especially which were prepared by freeze drying have started gaining popularity because this dosage forms disintegrate and dissolve rapidly. So this dosage form are suitable in elderly people suffering ostheoarhtitis and mus kuloskletal disorder who need piroxicam for their therapy. This research studied the effect of gelatin concetration on physical charateristics (hardness, friability and disi ntegration time) and di ssolution profiles of piroxicam ODTs prepared by freeze drying. Result showed that tablets containing gelatin 1% have better mechanical strength and dissolution compared to those tablets containing gelatin 2%. In spite of all formulations were disintegrated under 30 seconds in water medium at 37 o C
| Item Type: | Thesis (Skripsi) | |||||||||
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| Additional Information: | KKB KK-2 FF 326 11 Dew p | |||||||||
| Uncontrolled Keywords: | PIROXICAM ; TABLETS | |||||||||
| Subjects: | R Medicine > RS Pharmacy and materia medica | |||||||||
| Divisions: | 05. Fakultas Farmasi > Farmastika | |||||||||
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| Depositing User: | Dwi Marina | |||||||||
| Date Deposited: | 27 Jan 2012 12:00 | |||||||||
| Last Modified: | 25 Jul 2016 03:19 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/9608 | |||||||||
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