YUNIAWATI, 050911131 (2013) SINTESIS 6- (4-METILPIPERAZIN-1-ILMETIL) PINOSTROBIN MELALUI REAKSI MANNICH DENGAN MATERIAL AWAL PINOSTROBIN. Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
The aim of this study was to synthesize 6-(4-methylpiperazine-1- ilmetil)pinostrobin as target compound by Mannich reaction. As secondary amine, 1-methylpiperazine was reacted with formalin to form iminium salt. The target compound was synthesized by reacting the iminium salt with pinostrobin in three different reaction times, that are 1 hour, 3 hours and 5 hours, respectively. The structure of 6-(4-methylpiperazine-1- ilmetil)pinostrobin was confirmed by IR and 1H-NMR spectroscopy. The highest percentage yield of 15% was obtained in 5 hours of reaction time.
| Item Type: | Thesis (Skripsi) | ||||||
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| Additional Information: | KKB KK-2 FF.KF 54/13 Yun s | ||||||
| Uncontrolled Keywords: | MANNICH REACTION | ||||||
| Subjects: | Q Science > Q Science (General) > Q1-390 Science (General) Q Science > QD Chemistry > QD1-999 Chemistry |
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| Divisions: | 05. Fakultas Farmasi > Kimia Farmasi | ||||||
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| Depositing User: | shiefti dyah alyusi | ||||||
| Date Deposited: | 08 Jan 2014 12:00 | ||||||
| Last Modified: | 11 Aug 2016 05:18 | ||||||
| URI: | http://repository.unair.ac.id/id/eprint/9746 | ||||||
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