Isolation of cytotoxic sesquiterpenes from Curcuma comosa and characterization of their structures

Khun Nay Win Tun and Nanik Siti Aminah and Alfinda Novi Kristanti and Rico Ramadhan and Yoshiaki Takaya and HninThanda Aung (2019) Isolation of cytotoxic sesquiterpenes from Curcuma comosa and characterization of their structures. Journal of Indian Chemical Society, 96 (12). pp. 1513-1517. ISSN 00194522

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Abstract

Abstract: This research expresses the phytochemical study from the Myanmar edible fruit tree, Casimiroa edulis (Rutaceae). The result revealed that the isolation and identification of two furanocoumarins (bergapten 1 and isopimpinellin 2) from the stem bark of this plant. Their molecular structures were elucidated and identified by using NMR spectroscopy in combination with IR, UV and HRMS spectra data, respectively. Furthermore, these two compounds were investigated for their anti-diabetic activity. According to the result, bergapten 1 and isopimpinellin 2 are not essentially good for anti-diabetic activity. This is the first report of two furanocoumarins from the Myanmar edible fruit tree.

Item Type: Article
Uncontrolled Keywords: Casimiroa edulis, Furanocoumarins, NMR spectroscopy, anti-diabetic activity
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Khun Nay Win TunUNSPECIFIED
Nanik Siti AminahNIDN0014056707
Alfinda Novi KristantiNIDN0015116702
Rico RamadhanUNSPECIFIED
Yoshiaki TakayaUNSPECIFIED
HninThanda AungUNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 18 Sep 2020 02:39
Last Modified: 18 Sep 2020 02:39
URI: http://repository.unair.ac.id/id/eprint/98013
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