Alfarius E. Nugroho, - and Masatomo Sugai, - and Yusuke Hirasawa, - and Takahiro Hosoya, - and Khalijah Awang, - and A. Hamid A. Hadi, - and Wiwied Ekasari, - and Aty Widyawaruyanti, - and Hiroshi Morita, - (2011) New antiplasmodial indole alkaloids from Hunteria zeylanica. Bioorganic & Medicinal Chemistry Letters, 21 (11). pp. 3417-3419. ISSN 0968-0896

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Abstract

Two new indole alkaloids, bisnicalaterine D (1), consisting of an eburnane and a corynanthe type of skeletons, and nicalaterine A (2) were isolated from the bark of Hunteria zeylanica. Their structures were elucidated by various spectroscopic data such as NMR and CD spectra. A series of bisnicalaterines and nicalaterine A showed potent antiplasmodial activity against Plasmodium falciparum 3D7.

Item Type:	Article
Uncontrolled Keywords:	Indole alkaloid, Bisnicalaterine D, Nicalaterine A, Hunteria zeylanica, Antiplasmodial activity
Subjects:	R Medicine R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions:	05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:	Creators NIM Alfarius E. Nugroho, - - Masatomo Sugai, - - Yusuke Hirasawa, - - Takahiro Hosoya, - - Khalijah Awang, - - A. Hamid A. Hadi, - - Wiwied Ekasari, - NIDN0022016902 Aty Widyawaruyanti, - NIDN0026046210 Hiroshi Morita, - -
Depositing User:	Mr M. Fuad Sofyan
Date Deposited:	30 May 2022 04:02
Last Modified:	31 Mar 2023 08:00
URI:	http://repository.unair.ac.id/id/eprint/100938
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