Aty Widyawaruyanti, - and Uswatun Khasanah, - and Lidya Tumewu, - and Hilkatul Ilmi, - and Achmad Fuad Hafid, - and Indah Setyawati Tantular, - (2014) In Vivo Antimalarial Activity of Ethanol Extract and Ethyl Acetate Fraction of Alectryon serratus Leaves on Plasmodium berghei Infected Mice. In: Proceeding the 1st International Conference on Pharmaceutics and Pharmaceutical Sciences. Universitas Airlangga, Surabaya, pp. 30-32. ISBN 978-602.72333-0-0

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Abstract

Malaria was a major global public health concern due to the development of resistance by the most lethal causative species, Plasmodium falciparum. Natural products were potential sources of new antimalarial drugs (Bero, 2011; Nogueira, 2011). In vitro antimalarial activity screening of several Indonesian plants using HRP2 method showed that ethanol extract and ethyl acetate (EA) fraction of Alectryon serratus were active as an antimalarial (Widyawaruyanti, 2014). The aim of this study is to identify Thin Layer Chromatography (TLC) profile and investigate in vivo antimalarial activity of extract and fraction of Alectryon serratus leaves.

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