CYTOTOXIC CONSTITUENT IN THE FRUIT PEEL OF Lansium domesticum

Q. Labibah, .- and K. N. W. Tun, .- and N. S. Aminah*, .- and A. N. Kristanti, .- and R. Ramadhan, .- and Y. Takaya, .- and C. A. C. Abdullah, .- and M. J. Masarudin, .- (2021) CYTOTOXIC CONSTITUENT IN THE FRUIT PEEL OF Lansium domesticum. Rasayan JOURNAL OF CHEMISTRY, 14 (2). pp. 1336-1340. ISSN 0974-1496 | e-ISSN: 0976-0083

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Abstract

Phytochemical study of the hexane fruits peel extract of Lansium domesticum contributed to the discovery of onoceranoid-type triterpene, onoceradienedione 1. The structure of the isolated compound was done by advance spectroscopic techniques, comprising IR, UV, 1D, 2D NMR and HR-ESI-MS spectra data. Moreover, hexane extract and isolated compound 1 were examined for their cytotoxic activity against HeLa, T47D, and A549 cells. The results revealed the significance cytotoxic activity in the hexane extract.

Item Type: Article
Uncontrolled Keywords: Fruit Peel, Onoceranoid-type triterpene, Meliaceae, Cytotoxicity, Anticancer, Spectroscopic Analysis
Subjects: Q Science
Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Q. Labibah, .-UNSPECIFIED
K. N. W. Tun, .-UNSPECIFIED
N. S. Aminah*, .-0014056707
A. N. Kristanti, .-UNSPECIFIED
R. Ramadhan, .-UNSPECIFIED
Y. Takaya, .-UNSPECIFIED
C. A. C. Abdullah, .-UNSPECIFIED
M. J. Masarudin, .-UNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 01 Sep 2021 04:41
Last Modified: 29 Sep 2021 09:23
URI: http://repository.unair.ac.id/id/eprint/109931
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