Yusuke Hirasawa, - and Hiroko Arai, - and Abdul Rahman, - and Idha Kusumawati, - and Noor Cholies Zaini, - and Osamu Shirota, - and Hiroshi Morita, - (2013) Voacalgines AeE, new indole alkaloids from Voacanga grandifolia. Tetrahedron, 69 (51). pp. 10869-10875. ISSN 1464-5416

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Abstract

Five new indole alkaloids, voacalgines A–E (1–5) consisting of a C-mavacurine type of skeleton with 2,3-dihydroxybenzoate moiety, a macroline-type of skeleton, or a macroline-type of skeleton with C6 unit, were isolated from the bark of Voacanga grandifolia. Their relative structures were determined by means of NMR data. Voacalgine A showed moderate cell growth inhibitory activities against HL-60 and HCT116 cells.

Item Type:	Article
Uncontrolled Keywords:	Indole alkaloid, Voacanga grandifolia, Voacalgine A, Cytotoxicity
Subjects:	R Medicine R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions:	05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:	Creators NIM Yusuke Hirasawa, - - Hiroko Arai, - - Abdul Rahman, - - Idha Kusumawati, - NIDN0004087003 Noor Cholies Zaini, - - Osamu Shirota, - - Hiroshi Morita, - -
Depositing User:	Mr M. Fuad Sofyan
Date Deposited:	08 Jul 2022 01:59
Last Modified:	26 Mar 2023 07:47
URI:	http://repository.unair.ac.id/id/eprint/116993
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