Ayub Manggala Putra, Ayub and Lailatul Muqmiroh, Lailatul and Budi Prijo Witjaksono, Budi and Rosy Setiawati, Rosy and Amilia Kartikasari, Amilia and Pham Minh Thong, Pham and Vu Dang Luu, Vu and Cong Tien Nguyen, Cong and Phan Anh Phuong, Phan and Le Van Chuyen5, Le (2020) A Comparative Study Between Filtered Back Projection (FBP) and Sinogram-Affirmed Iterative (SAFIRE) Reconstructions on HRCT Chest of COPD Patients to Measure the Quantity of Emphysema and Lung Volumes. Malaysian Journal of Medicine and Health Sciences, 6. pp. 19-23. ISSN 2636-9346

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Abstract

ABSTRACT Introduction: Chest High Resolution Computed Tomography (HRCT) plays a role in determining the emphysema severity levels of COPD patients by measuring the low-attenuation volume (LAV) of the lung parenchyma. Methods: This can be used as an alternative to calculate the lung volumes and provide additional information on the pathology that causes both the increase and the decrease of lung volumes. Generally, the reconstruction of raw data in HRCT uses Filtered Back Projection (FBP). Nowadays, reconstruction technology that can be used as an alternative for HRCT is reconstruction iterative (IR) to maximize the diagnosis information and the image quality in a low radiation dose. Sinogram-Affirmed Iterative Reconstruction (SAFIRE) is an iterative reconstruction using noise modelling technique. The research aimed at comparing the use of FBP reconstruction using SAFIRE to measure the quantity emphysema and lung volumes. Results: A reconstruction using window lung filter kernel B70f sharp and reconstruction using SAFIRE soft tissue standard l70f sharp were performed to 40 samples. A post-processing, then, was conducted to each of the reconstruction result to measure the quantity of emphysema by displaying the Low Attenuation Volume (LAV%) values and lung volumes (ml). Conclusion: The result of the research shows that the use of reconstruction using SAFIRE can affect the measurement result of the quantity of emphysema and lung volumes quantitatively by using a post-processing software when compared to the reconstruction using FBP with the significant values (p<0,05)

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