Paulus Sugianto, Paulus and Abdulloh Machin, - and Devi Ariani Sudibyo, - and Muhammad Hamdan, - Correlation between Blood and Cerebrospinal Fluid (CSF) Neutrophil-Lymphocyte Ratio With Bacterial Meningitis Prognosis Patient. Jurnal Aisyah: Jurnal Ilmu Kesehatan, 8 (2). ISSN 2502-4825; eISSN: 2502-9495

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Abstract

Abstract Bacterial Meningitis is a bacterial infection of the central nervous system’s protective membranes called the meninges. Bacterial Meningitis has a high disability and case fatality rate. This inflammatory process not only manifests in CSF but also systemically. The neutrophil-lymphocyte ratio(NLR) can be a predicting factor of severity and prognosis in systemic inflammation. Only a few studies in Indonesia evaluate the neutrophil-lymphocyte ratio as a predictor of mortality in adult bacterial meningitis. This study also aimed to compare neutrophil-lymphocyte ratio in LCS and systemic as a predictor of mortality in patients with adult bacterial meningitis. This is an analytic cross-sectional study in Dr. Soetomo's general hospital—a total sample of 44 bacterial meningitis patients from the inpatient ward of Dr. Soetomo General Hospital Surabaya. The blood Neutrophil- Lymphocyte ratio, Glasgow Coma Scale upon admission, and Absolute lymphocyte count were significant with bacterial meningitis outcome with p-value less than 0.05. Early detection of bacterial meningitis patient prognosis could alert the healthcare provider to give careful monitoring and aggressive treatment.

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