NURIMA ADILAHSANIY, 051111138 (2016) AKTIVITAS ANTIKOLESTEROL KOMBINASI EKSTRAK KERING DAUN KUMIS KUCING (ORTHOSIPHON STAMINEUS BENTH.)DAN EKSTRAK KERING PERIKARPIUM MANGGIS(GARCINIA MANGOSTANA LINN.) TERHADAPMENCIT YANG DIINDUKSI ALOKSAN. Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
The rapid development of times recently, raises the negative effects, which one of it is eating pattern shift, from something balance and natural, to be monotonous and instant. The bad effect causes a tendency to consume high fatty foods more and more that causes the level of cholesterol higher. Hypercholesterolemia is the increasing of cholesterol level in blood. The high cholesterol level is the main risk factor to get a coronary heart disease. The uses of natural ingredients as traditional medicine have been widely public accepted almost all over the world. This is the reason why the use of traditional herbal as mangosteen pericarp and orthosiphon leaf is interesting to cope with hyperlipidemia and can be developed further as standardized herbal, especially to decrease cholesterol level. In this study, mice as experimental animals grouped into 6 groups: Normal Control; Negative Control; Positive Control; 11,65mg/20g bw:23,3mg/20g bw; 11,65mg/20g bw:11,65mg/20g bw;and 23,3mg/20g bw:11,65mg/20g bw. After test materiel exposing, bloods cholesterols levels have been evaluated at the 3rd, 5th, and 7th days. The cholesterol level analysis used one way ANOVA α=0,05 with LSD test and being concluded. The result of research showed that combination of dry extract of mangosteen pericarpand orthosiphon leaf is able to lower cholesterol level of mice alloxan induced with proportion of11,65mg/20g bw : 11,65mg/20g bw. This research is expected to support the further researches related to the benefits of mangosteen pericarp combined with orthosiphon leaf in the field of medicine
| Item Type: | Thesis (Skripsi) | ||||||
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| Additional Information: | KKB KK-2 FF FT.01/16 Adi a | ||||||
| Uncontrolled Keywords: | Garcinia mangostana Linn., Orthosiphon stamineus Benth., mangosteen, orthosiphon, anticholesterol, cholesterol, activity test | ||||||
| Subjects: | R Medicine > RS Pharmacy and materia medica | ||||||
| Divisions: | 05. Fakultas Farmasi > Farmakognosi Fitokimia | ||||||
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| Depositing User: | Unnamed user with email indah.fatma@staf.unair.ac.id | ||||||
| Date Deposited: | 22 Apr 2016 01:45 | ||||||
| Last Modified: | 22 Apr 2016 01:58 | ||||||
| URI: | http://repository.unair.ac.id/id/eprint/29709 | ||||||
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