PENGARUH OKSIGENASI HIPERBARIK TERHADAP AKTIFITAS RADIKAL BEBAS DARAH PRA USIA LANJUT

YOSI YUDYA SATRIA, 099813009 M (2001) PENGARUH OKSIGENASI HIPERBARIK TERHADAP AKTIFITAS RADIKAL BEBAS DARAH PRA USIA LANJUT. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Official URL: http://lib.unair.ac.id

Abstract

The influence of Hyperbaric Oxygenation on blood Reactive Oxygen Species (ROS), Superoxyde dismutase (SOD), Malondialdehyde (MDA) on healthy pre-old women was investigated. An experimental laboratory study was performed at Naval Health Institution in Surabaya. Nine healthy women were exposed to 100% 02 at 2,4 ATA, 3x30 minutes with interval 5 minutes breathing air, once a day on five consecutive days, and nine healthy pre-old women as control with normoksia normobaric. The blood ROS, SOD, and MDA were evaluated before the first session, after the third session and after the fifth session HBO exposures. The measurement of ROS using luminometri basicly by chemiluminescence and measurement SOD and MDA using spectrophotometry. On HBO group, was observed ROS decreased significantly after the third session (p<0,05), from ( 274,2222 ± 35,2468 ) before the first session to ( 152,3333 ± 20,9666 ) after the third session, and did not increased significantly (p?0,05) to (209,0000 ± 23,6814 ) after the fifth session. In this group SOD did not decreased significantly (p>_0,05) from (13,462 ± 0,1608 ) before the session to ( 12,780 ± 0,3566 ) after the third session, and increased not significantly (p_>0,05) after the fifth session (13,419 ± 0,3615 ). And MDA decreased significantly (p<0,05) from (2,35222 ± 0,1090) before the first session to (1,2022 ± 0,0815) after the third session, and increased significantly (p<0,05) after the fifth session (1,5467 ± 0,0946). On the control group all evaluated parameters did not differ significantly. Conclusion: ROS decreased significantly on OHB group compared with control group, SOD increased not significantly on OHB group compared with control group, MDA decreased not significantly on OHB group compared with control.

Item Type: Thesis (Thesis)
Additional Information: KKA KK TKD 39/01 Sat p
Uncontrolled Keywords: Hyperbaric Oxygenation, Reactive Oxygen Species, Superoxyde dismutase, Malondialdehyde
Subjects: H Social Sciences > HV Social pathology. Social and public welfare > HV1-9960 Social pathology. Social and public welfare. Criminology > HV697-4959 Protection, assistance and relief > HV697-3024 Special classes > HV1450-1494 Aged
R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine
R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine > RA565-600 Environmental health
Divisions: 09. Sekolah Pasca Sarjana > Ilmu Kedokteran Dasar
Creators:
CreatorsNIM
YOSI YUDYA SATRIA, 099813009 MUNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorPurnomo Suryohudoyo, Prof.,dr.,DBSKUNSPECIFIED
Thesis advisorSunarko Setyawan, Dr.,dr.,MSUNSPECIFIED
Depositing User: Nn Anisa Septiyo Ningtias
Date Deposited: 2016
Last Modified: 10 Aug 2016 03:14
URI: http://repository.unair.ac.id/id/eprint/35763
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