EFEKTIVITAS PEMBERIAN LEUCOVORIN TERHADAP KADAR 5-MTHF (5-Methyltetrahydrofolate) SETELAH TERAPI METOTREKSAT DOSIS TINGGI PASIEN ANAK LEUKEMIA LIMFOBLASTIK AKUT (Penelitian dilaksanakan di Divisi Hematologi-Onkologi SMF Ilmu Kesehatan Anak RSUD Dr. Soetomo Surabaya) Repository

EFEKTIVITAS PEMBERIAN LEUCOVORIN TERHADAP KADAR 5-MTHF (5-Methyltetrahydrofolate) SETELAH TERAPI METOTREKSAT DOSIS TINGGI PASIEN ANAK LEUKEMIA LIMFOBLASTIK AKUT (Penelitian dilaksanakan di Divisi Hematologi-Onkologi SMF Ilmu Kesehatan Anak RSUD Dr. Soetomo Surabaya)

YUFITA RATNASARI WILIANTO, 051715153020 (2019) EFEKTIVITAS PEMBERIAN LEUCOVORIN TERHADAP KADAR 5-MTHF (5-Methyltetrahydrofolate) SETELAH TERAPI METOTREKSAT DOSIS TINGGI PASIEN ANAK LEUKEMIA LIMFOBLASTIK AKUT (Penelitian dilaksanakan di Divisi Hematologi-Onkologi SMF Ilmu Kesehatan Anak RSUD Dr. Soetomo Surabaya). Thesis thesis, Universitas Airlangga.

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Official URL: Http:///lib.unair.ac.id

Abstract

One of the cytotoxicity of high-dose methotrexate is the occurrence of 5-MTHF depletion in the body. Leucovorin can be used to selectively “rescue” cells from the adverse effects of methotrexate. Leucovorin supplies the necessary cofactor blocked by methotrexate, enters the cells via the same active transport system as methotrexate.

Item Type:

Thesis (Thesis)

Additional Information:

KKB KK TFK 25/19 Wil e

Uncontrolled Keywords:

Acute Lymphoblastic Leukemia (ALL), Leucovorin, 5-MTHF (5- Methyltetrahydrofolate), High-Dose Methotrexate (HD-MTX).

Subjects:

R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica

Divisions:

05. Fakultas Farmasi > Farmasi Klinis

Creators: