Macagigantin, a farnesylated flavonol from Macaranga gigantea

Mulyadi Tanjung and Euis H. Hakim and Didin Mujahidin and Muhammad Hanafi and Yana M. Syah (2009) Macagigantin, a farnesylated flavonol from Macaranga gigantea. Journal of Asian Natural Products Research, 11 (11). pp. 929-932. ISSN 1028-6020

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Official URL: https://www.tandfonline.com/doi/abs/10.1080/102860...

Abstract

A new farnesylated flavonol derivative, macagigantin (1), together with two known flavonoids, glyasperin A (2) and apigenin (3), had been isolated from the acetone extract of the leaves of Macaranga gigantea. The structure of the new compound was elucidated as 6-farnesylkaempferol based on its spectroscopic data, including UV, IR, 1D and 2D NMR, and HR-EI-MS spectra. Compounds 1–3 were evaluated for their cytotoxic properties against P-388 cells, their IC values being 11.3, 6.0, and 5.1 mM, respectively.

Item Type: Article
Uncontrolled Keywords: macagigantin; farnesylated flavonol; Macaranga gigantea; Euphorbiaceae; cytotoxicity; P-388 cells
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Mulyadi TanjungNIDN0022046503
Euis H. HakimUNSPECIFIED
Didin MujahidinUNSPECIFIED
Muhammad HanafiUNSPECIFIED
Yana M. SyahUNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 2015
Last Modified: 13 Mar 2020 02:57
URI: http://repository.unair.ac.id/id/eprint/90941
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