Muchammad Manhum Mawarid (2020) Potensi Ekstrak Rumput Kebar (Biophytum petersianum) Terhadap Gambaran Histopatologi Duodenum Induk Mencit (Mus musculus) Masa Laktasi Yang Dipapar Karbofuran. Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
The aims of this study were to find the effect of extract of kebar grass on decreasing inflammation effect and toxic damage in the lactation stage mice's duodenum by exposure to carbofuran. This research used fourty-two of lactation stage mice, divided into seven treatment groups, each group contain six mice. Treatment groups consists of K (aquadest); P1 (carbofuran 1/4 LD50 0.0125 mg/day) ; P2 (carbofuran 1/8 LD50 0,00625 mg/day) ; P3 ( grass kebar extract 3.375 mg 0.2 ml + carbofuran 1/4 LD50 ) ; P4 ( grass kebar extract 3.375 mg 0.2 ml + carbofuran 1/8 LD50 ) ; P5 ( vitamin C 5 mg 0.2 cc + carbofuran 1/4 LD50 ) ; P6 ( vitamin C 5 mg 0.2 cc + carbofuran 1/8 LD50 ). P1, P2, P3, P4, P5, and P6, each of group given with carbofuran for 14 days with different dose. Observation with measurement of the pathology histology of mice's duodenum. The result was analyzed with kruskal-wallis test and Mann-whitney test with significant difference between each treatment group. The conclusion of this study showed that is increasing carbofuran dose linear with increase of histopatologic damage such as damage at Vili, congestion, oedema, and neutrofile infiltritation (p<0.05). Kebar grass at 3.375 mg 0.2 ml dose which is P3 and P4 could decrease inflammation effect and toxic effect more than vitamin C 5 mg 0.2 cc or P5 and P6 (p<0.05).
| Item Type: | Thesis (Skripsi) | |||||||||
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| Additional Information: | KKC KK KH 09-21 Maw p | |||||||||
| Uncontrolled Keywords: | Kebar Grass Extract, Carbofuran, Lactation Period, Duodenum | |||||||||
| Subjects: | S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF780.2-780.7 Veterinary microbiology, bacteriology, virology, mycology S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF811-909 Veterinary medicine of special organs, regions, and systems |
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| Divisions: | 06. Fakultas Kedokteran Hewan > Ilmu Kedokteran Hewan Dasar | |||||||||
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| Depositing User: | prasetyo adi nugroho | |||||||||
| Date Deposited: | 08 Mar 2021 02:39 | |||||||||
| Last Modified: | 08 Mar 2021 02:39 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/104653 | |||||||||
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