Muhammad Luthfi, - and Tuti Kusumaningsih, - and Agung Sosiawan, - and Hasna Sabrina, - (2020) Anti-Inflammatory Effect of Okra (Abelmoschus esculentus) Fruit Extract during Wound Healing Process after Tooth Extraction of Diabetic Wistar Rat. Journal of International Dental and Medical Research, 13 (2). pp. 497-502. ISSN 1309100X

	Text (ARTICLE) Anti-Inflammatory Effect of Okra (Abelmoschus esculentus) Fruit Extract.pdf Download (395kB)
	Text (SIMILARITY) Anti-Inflammatory Effect of Okra (Abelmoschus esculentus) Fruit Extract during Wound Healing Process after Tooth Extraction of Diabetic Wistar Rat.pdf Download (2MB)
	Text (TURNITIN) 13. Anti-Inflammatory Effect of Okra (Abelmoschus esculentus) Fruit Extract during Wound Healing Process after Tooth Extraction of Diabetic Wistar Rat.pdf Download (2MB)
	Text (PEER REVIEW) Anti – Inflammatory Effect.pdf Download (400kB)
	Text (VALIDASI2) c-13.pdf Download (3MB)
	Text (PENILAIAN) 13. PENILAIAN KARIL DAN BIDANG ILMU.pdf Download (367kB)

Abstract

To analyze the anti-inflammatory properties of okra fruit extract and its efffect toward wound healing process in diabetic mellitus rats. 27 Wistar rats were divided into three groups: (1) negative control (K-), (2) positive control (K+) and (3) streptozotocin induction and 250 mg/kg body weight okra fruit extract (P). Three rats from each group were sacrificed on the 1st, 4th, and 7th days after extraction of their left lower incisor and excised for histologic examination by Hematoxylin Eosin (HE) staining to enable evaluation of the neutrophil expressions. The administration of okra extract to the tooth extraction wounds significantly reduced neutrophil expression compared to that in the untreated group. There was a significant difference on day 1 between the following groups: (1) K- and K+ and (2) K + and P. On day 4, the most significant difference was between K- and P. On day 7, the most significant difference was between K- and K+ group, K+ and P group. Okra fruit extract exhibits anti-inflammatory activity and is, therefore, an effective agent for healing process of tooth extraction wounds in diabetic mellitus rats.

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