Iwan Sahrial Hamid, - and Ngakan Made Rai Widjaja, - (2020) Antiangiogenesis Activity of Centella Asiatica on the Macrophage Number and Matrix Metalloproteinase-9 in Blood Vessels of Chorioallantois Membrane Induced by Basic Fibroblast Growth Factor. Indian Veterinary Journal, 97 (2). pp. 17-20. ISSN 0019-6479, E-ISSN 0974-9365
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Abstract
This study aimed to examine the potential of aqueous extract of Centella asiatica on the macrophage number and matrix metalloproteinase-9 (MMP-9) in blood vessels of chorioallantois membrane induced by basic Fibroblast Growth Factor (bFGF). This study used 20 embryonated chicken eggs (ECE) which were divided into five groups i.e. positive control (C+) given 60 ng of bFGF; negative control (C-) given DMSO 2%; treatment groups (T1; T2; T3) given 60 ng of bFGF and Centella asiatica extract (75; 90; 110) μg. It was concluded that Centella asiatica at a dose of 110 μg decreased the macrophage number and the expression of MMP-9 Key words: Centella asiatica, Chorioallantois membrane, Macrophage, MMP-9
Item Type: | Article | ||||||
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Uncontrolled Keywords: | Centella asiatica, Chorioallantois membrane, Macrophage, MMP-9 | ||||||
Subjects: | S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF811-909 Veterinary medicine of special organs, regions, and systems | ||||||
Divisions: | 06. Fakultas Kedokteran Hewan > Ilmu Kedokteran Hewan Dasar | ||||||
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Depositing User: | Nn Erna Dwi Indriyani | ||||||
Date Deposited: | 27 May 2021 02:39 | ||||||
Last Modified: | 30 Dec 2021 03:07 | ||||||
URI: | http://repository.unair.ac.id/id/eprint/107229 | ||||||
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