Muhammad Luthfi, - and Wisnu Setyari Juliastuti, - and Yuniar Aliyah Risky, - (2020) Angiogenesis of Extracted Tooth Wound on Wistar Rats After Application of Okra (Abelmoschus esculentus) Gel Extract. Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 20. pp. 1-8. ISSN 1519-0501

	Text (ARTIKEL) Angiogenesis of Extracted Tooth Wound.pdf Download (980kB)
	Text (SIMILARITY) 3. Angiogenesis of Extracted Tooth Wound on Wistar Rats After Application of Okra (Abelmoschus esculentus) Gel Extract.pdf Download (2MB)
	Text (VALIDASI) 3.Dr.Luthfi (Angiogenesis of Extracted...).pdf Download (935kB)
	Text (PENELITIAN) 3. Kualitas Karil dan Kesesuaian Bidang Ilmu.pdf Download (532kB)
	Text (PENELITIAN 2) 3. Kualitas Karil dan Kesesuaian Bidang Ilmu.pdf Download (532kB)
	Text (KORESPONDEN) 2. Angiogenesis of Extracted Tooth Wound on Wistar Rats After Application of Okra (Ab.pdf Download (688kB)
	Text (KORESPONDEN) 12.pdf Download (2MB)
	Text (BUKTI KORESPONDEN 1) 1.Angiogenisis.pdf Download (797kB)

Abstract

Objective: To analyze angiogenesis in the post-extracted tooth of Wistar rats after application of okra (Abelmoschus esculentus) extract. Material and Methods: A total of 18 rats were divided into two groups (control and treatment). Okra extract with a concentration of 30% in gel form was applied on the postextraction socket of the treatment group. The rats were sacrificed on day-3, day-5, and day-7 after tooth extraction. The newly-formed blood vessels were counted and statistically analyzed by means of One Way ANOVA and Tukey HSD with a significance level set at 5%. Results: The newly-formed capillaries of the control group (4.67 ± 1.53) on day-3 were lower than the treatment group (9.00 ± 1.00). The newly-formed capillaries recorded from the control group, both in day-5 (9.33 ± 1.53) and day-7 (8.67 ± 1.53) were lower than the treatment group, which started to decreased from day-5 (13.67 ± 1.53) to day-7 (12.33 ± 0.58). Significant differences were found in treatment group, on day-3 compared to day-5 (p=0.005), and on day-3 to day-7 (p=0.024). Conclusion: Okra extract in gel form at 30% concentration can increase the angiogenesis during the wound healing process of the extracted tooth on Wistar rats.

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