Cassiarins C-E, Antiplasmodial Alkaloids from the Flowers of Cassia siamea

Shiori Oshimi, - and Jun Deguchi, - and Yusuke Hirasawa, - and Wiwied Ekasari, - and Aty Widyawaruyanti, - and Tutik Sri Wahyuni, - and Noor Cholies Zaini, - and Osamu Shirota, - and Hiroshi Morita, - (2009) Cassiarins C-E, Antiplasmodial Alkaloids from the Flowers of Cassia siamea. Journal of Natural Products, 72 (10). pp. 1899-1901. ISSN 0163-3864

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Official URL: https://pubs.acs.org/doi/10.1021/np9004213

Abstract

Three new alkaloids, cassiarins C-E (1-3), and a new chromone, 10,11-dihydroanhydrobarakol (4), which showed moderate antiplasmodial activity against Plasmodium falciparum 3D7, were isolated from flowers of Cassia siamea, and the structures of 1-4 were elucidated by 2D NMR analysis and chemical transformation. Cassiarin D (2) was a dimeric compound consisting of 5-acetonyl-7-hydroxy-2-methylchromone and cassiarin C (1), and cassiarin E (3) was a dimer of cassiarins A and C (1).

Item Type: Article
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM
Shiori Oshimi, --
Jun Deguchi, --
Yusuke Hirasawa, --
Wiwied Ekasari, -NIDN0022016902
Aty Widyawaruyanti, -NIDN0026046210
Tutik Sri Wahyuni, -NIDN0025107704
Noor Cholies Zaini, --
Osamu Shirota, --
Hiroshi Morita, --
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 30 May 2022 02:42
Last Modified: 02 Aug 2022 08:20
URI: http://repository.unair.ac.id/id/eprint/116549
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