Harapan, - and Jonny Karunia Fajar, - and Supriono, - and Gatot Soegiarto, - and Laksmi Wulandari, - and Fiha Seratin, - and Nyoman Gede Prayudi, - and Dara Puspita Dewi, - and Maria Theresia Monica Elsina, - and Lasarus Atamou, - and Sinta Wiranata, - and Dhito Pemi Aprianto, - and Erlin Friska, - and D Fitria Sari Firdaus, - and Makdum Alaidin, - and Firdha Aprillia Wardhani, - and Milda Husnah, - and Nurdina Wahyu Hidayati, - and Yeni Hendriyanti, - and Kristia Wardani, - and Arde Evatta, - and Reizal Audi Manugan, - and Wiryawan Pradipto, - and Ade Rahmawati, - and Fredo Tamara, - and Aditya Indra Mahendra, - and Firzan Nainu, - and Budi Santoso, - and Chandra Adi Irawan Primasatya, - and Nindy Tjionganata, - and Hendarto Arif Budiman, - (2021) The prevalence, predictors and outcomes of acute liver injury among patients with COVID-19: A systematic review and meta-analysis. Reviews in Medical Virology, 32 (3). pp. 1-8. ISSN 10529276

	Text (Bukti Korespondensi) 2. Korespondensi_Artikel 19.pdf Download (1MB)
	Text (Peer Review) Karil Artikel 19.pdf Download (658kB)
	Text (Artikel) 1. Full Text_ Asrtikel 19.pdf Download (4MB)
	Text (Similarity) 3. Turnitin_Artikel 19.pdf Download (1MB)
	Text (Peer Review) 1.Karil_16.pdf Download (361kB)

Abstract

The data on the predictors and prognosis of acute liver injury (ALI) among patients in coronavirus disease 2019 (COVID-19) patients are limited. The aim of this study was to determine the prevalence, predictors and outcomes of ALI among patients with COVID-19. A systematic review was conducted up to 10 June 2021. The relevant papers were searched from PubMed, Embase, Cochrane and Web of Science, and the data were analysed using a Z test. A total of 1331 papers were identified and 16 papers consisting of 1254 COVID-19 with ALI and 4999 COVID-19 without ALI were analysed. The cumulative prevalence of ALI among patients with COVID-19 was 22.8%. Male and having low lymphocyte levels were more likely to be associated with ALI compared with female and having higher lymphocyte level, odds ratio (OR): 2.70; 95% confidence interval (CI): 2.03, 3.60 and mean difference (MD) −125; 95% CI: −207, −43, respectively. COVID-19 patients with ALI had higher risk of developing severe COVID-19 compared with those without ALI (OR: 3.61; 95% CI: 2.60, 5.02). Our findings may serve as the additional evaluation for the management of ALI in COVID-19 patients.

Actions (login required)

View Item