Devy Trianne Putri, - and Isnin Anang Marhana, - and Dhihintia Jiwangga, - (2020) Lung Pseudomesothelioma in Patient with Asbestos Exposure: A Case Report. Jurnal Respirasi, 6 (2). pp. 40-44. ISSN 2407-0831

	Text (Similarity) Similarity 8.pdf Download (2MB)
	Text (Artikel) Artikel 8.pdf Download (348kB)
	Text (Karil) Karil 8.pdf Download (164kB)

Abstract

Background: Pseudomesotheliomatous carcinoma is a rare case of lung cancer with marked pleural extension resembling malignant pleural mesothelioma on diagnostic imaging. One of tool to diagnose lung pseudomesothelioma is by performing thorocoscopy pleural biopsy. Diagnostic thoracoscopy also has a higher sensitivity than pleural fluid cytology and needle biopsy. Case: We report a rare case of pseudomesotheliomatous carcinoma of the lung in a 50-year-old man with asbestos exposure. The patient had complained of dyspnea and chest roentgenogram showed left pleural effusion. Computed tomography (CT) of the chest revealed diffuse irregular left pleural thickening and without a clear initial primary lesion found in both of lung parenchyma, which mimicked pleural mesothelioma. Pleural tissue sampling was performed to obtain definitive diagnosis by video-assisted thoracoscopic surgery. At the operation, the tumor was found to have spread along the pleural surface and primary lesion was not detected in the right lung parenchyma. Immunohistochemically, the tumor was positive for Thyroid Transcription Factor- 1 (TTF-1), but negative for calretinin, P63, and Neuron Specific Enolase (NSE). Final diagnosis was adenocarcinoma of the lung and patient had good clinical response to Gefitinib. Conclusion: Based on the results of clinical studies (images and clinical observations), although pseudomesotheliomatous in patient with asbestos exposure is difficult to distinguish from pleural mesothelioma, we have a case of pseudomesotheliomatous lung diagnosed by a thoracoscopic pleura biopsy. For such cases, thoracoscopic pleural biopsy should be performed at an early stage.

Item Type:	Article
Uncontrolled Keywords:	Pseudomesotheliomatous, Adenocarcinoma, Asbestos Exposure, Thoracoscopic Biopsy
Subjects:	R Medicine > R Medicine (General) R Medicine > RC Internal medicine > RC705-779 Diseases of the respiratory system
Divisions:	01. Fakultas Kedokteran > Ilmu Penyakit Paru
Creators:	Creators NIM Devy Trianne Putri, - UNSPECIFIED Isnin Anang Marhana, - NIDN8805800016 Dhihintia Jiwangga, - UNSPECIFIED
Depositing User:	arys fk
Date Deposited:	14 Feb 2023 07:22
Last Modified:	14 Feb 2023 07:22
URI:	http://repository.unair.ac.id/id/eprint/119965
Sosial Share:

Actions (login required)

View Item