SIDE EFFECTS OF METHOTREXATE FOR PSORIASIS THERAPY Repository

SIDE EFFECTS OF METHOTREXATE FOR PSORIASIS THERAPY

Melida Agustina, Melida and Afif Nurul Hidayati, Afif and Nurina Hasanatuludhhiyah, Nurina SIDE EFFECTS OF METHOTREXATE FOR PSORIASIS THERAPY. Berkala Ilmu Kesehatan Kulit dan Kelamin, 32 (2). ISSN 1978-4279

	Text (Artikel) 21. artikel.pdf Download (1MB)
	Text (Turnitin) 21. SIDE EFFECTS OF METHOTREXATE FOR PSORIASIS THERAPY.pdf Download (1MB)
	Text (Kualitas Karil & Kesesuaian Bidang Ilmu) 21. SIDE EFFECTS OF METHOTREXATE FOR PSORIASIS THERAPY.pdf Download (255kB)

Official URL: https://e-journal.unair.ac.id/BIKK/article/view/15...

Abstract

ABSTRACTBackground: Psoriasis is a chronic and relapsing inflammatory disease of the skin, characterized by the presence of well-defined erythematous plaque covered by silvery-white scales. Methotrexate is a folic acid antimetabolic for psoriasis therapy and given systemically so unexpected effects can occur. Purpose:To evaluate the side effects of methotrexate as therapy in psoriasis. Methods:The descriptive research based on the medical record of psoriasis patients who were treated for hospitalization on at Kemuning I and II ward Dr. Soetomo General Academic Hospital Surabaya during the period January 2017 – December 2018. The sampling method used was total sampling.Result: Twenty two psoriasis patients receiving methotrexate therapy with the dose of methotrexate is 10-15 mg once weekly, there were 4.5% low erythrocyte level, 27.3% high leukocyte level, 13.6% high thrombocyte level, 18.2% high SGOT level, 22.8% high SGPT level, 18% nausea, 9.1% vomiting, 4.6% headache, and 4.6% shortness of breath. Conclusion: Methotrexate for psoriasis therapy may cause several side effects even not the severe ones, therefore careful dosing and side effect monitoring are necessary

Item Type:

Article

Subjects:

R Medicine > R Medicine (General) > R5-920 Medicine (General)

Divisions:

01. Fakultas Kedokteran > Ilmu Kesehatan Kulit dan Kelamin (Spesialis)

Creators: