Djoko Santoso, Djoko and I Ketut Sudiana, I Ketut and Anny Setijo Rahaju, Anny and Muchammad Yunus, Muchammad Effect of Ethanolic Extract of Cayratia trifolia on Histologically Kidney Mouse Model. In: Effect of Ethanolic Extract of Cayratia trifolia on Histologically Kidney Mouse Model. Universitas Brawijaya.
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Abstract
Abstract This study was conducted to determine the effect of Cayratia trifolia ethanolic extract on histological mouse kidney models. A total of 12 adult male Balb/c mice were randomly divided into two groups, comprising six mice in each group. The first group of 6 mice provided as the control group and received 25 ml/kg BW orally sodium carboxymethylcellulose during 6 days.The second group, 6 mice was administered 50 mg/kg BW of C. trifolia ethanolic extract in sodium carboxymethylcellulose orally during 6 days. The present study, we have performed histological kidney mice evaluation after 6 days of C. trifolia ethanolic extract administration. The histological mice kidney was quantified in term of tubular epithelium, glomerular and focal mononuclear infiltrate. The effect of administration of C. trifolia ethanolic extract on histological kidney of mice appeared normal tubular morphology in cortical and medullary regions of kidney in administered C. trifolia ethanolic extract mice, there was no kidney change histologically showed normal architecture of the glomerulus and tubules, while in control mice group, kidney histologically first marked with mononuclear cell infiltration, tubular necrosis, glomerular congestion and hyaline casts. The study results exhibit that relatively sufficient in histopathological changes in the corticomedullary junction of mice kidneys, including tubular epithelial damage, tubular dilatation and intratubular cast formation.
| Item Type: | Book Section | ||||||||||
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| Subjects: | R Medicine > R Medicine (General) > R5-920 Medicine (General) | ||||||||||
| Divisions: | 01. Fakultas Kedokteran > Patologi Anatomi | ||||||||||
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| Depositing User: | arys fk | ||||||||||
| Date Deposited: | 12 Apr 2023 00:41 | ||||||||||
| Last Modified: | 12 Apr 2023 00:41 | ||||||||||
| URI: | http://repository.unair.ac.id/id/eprint/123006 | ||||||||||
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