Farheen Badrealam Khan, - and Shahab Uddin, - and Abozer Y. Elderdery, - and Khang Wen Goh, - and Long Chiau Ming, - and Chrismawan Ardianto, - and Abdul Rasheed Palakot, - and Irfa Anwar, - and Mohsina Khan, - and Mohammad Owais, - and Chih-Yang Huang, - and Jayasimha Rayalu Daddam, - and Meraj Alam Khan, - and Shoaib, - and Md Khursheed, - and Sara Reshadat, - and Hamid Reza Khayat Kashani, - and Sameer Mirza, - and Abbas A. Khaleel, - and Mohammed Akli Ayoub, - (2022) Illuminating the Molecular Intricacies of Exosomes and ncRNAs in Cardiovascular Diseases: Prospective Therapeutic and Biomarker Potential. Cells, 11 (22). pp. 1-19. ISSN 2073-4409

	Text (FULLTEXT) Artikel C-36.pdf Download (8MB)
	Text (Kualitas Karil) (C-36) Kualitas Karil.pdf Download (575kB)
	Text (Similarity) Similarity C-36.pdf Download (6MB)

Abstract

Cardiovascular diseases (CVDs) are one of the leading causes of death worldwide. Accumulating evidences have highlighted the importance of exosomes and non-coding RNAs (ncRNAs) in cardiac physiology and pathology. It is in general consensus that exosomes and ncRNAs play a crucial role in the maintenance of normal cellular function; and interestingly it is envisaged that their potential as prospective therapeutic candidates and biomarkers are increasing rapidly. Considering all these aspects, this review provides a comprehensive overview of the recent understanding of exosomes and ncRNAs in CVDs. We provide a great deal of discussion regarding their role in the cardiovascular system, together with providing a glimpse of ideas regarding strategies exploited to harness their potential as a therapeutic intervention and prospective biomarker against CVDs. Thus, it could be envisaged that a thorough understanding of the intricacies related to exosomes and ncRNA would seemingly allow their full exploration and may lead clinical settings to become a reality in near future.

Actions (login required)

View Item