Lailatul Nuraini, - (2021) Pengaruh Proses Fermentasi Pada Daun Centella Asiatica Oleh Acetobacter Tropicalis Inacc B374 Terhadap Aktivitas Trombolitik. Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
Background: Thrombolytic Agents Are Plasminogen Activators That Can Be Used To Break Down Fibrin Into Fibrin Degradation Product In Cardiovascular Therapy. Thrombolytic Agents Can Be Sourced From Microorganisms Including Acetobacter Tropicalis Inacc B374 And Sourced From Plants Including Centella Asiatica. Both Sources Of Thrombolytic Agents Are Combined Through A Fermentation Process To Enhance Their Therapeutic Effect. Objectives: This Research Aimed To Find Out The Increase In Thrombolytic Activity From The Fermentation Product Of Centella Asiatica By Acetobacter Tropicalis Inacc B374 In The Variation Of Fermentation Time. Methods: Centella Asiatica Fermentation Process Was Carried For 24, 48, And 72 Hours At 30°±1°C. The Thrombolytic Activity Was Determined By The Clot Lysis Method. Results: The Results Of The Thrombolytic Investigation Showed That There Was An Increase In Thrombolytic Activity During The Fermentation Process. Centella Asiatica Fermented For 72 Hours Showed The Highest Thrombolytic Index (82,03) As Compared To Exhibited By Centella Asiatica (37,39) And Acetobacter Tropicalis Inacc B374 (37,68). Conclusion: This Study Revealed That The Fermentation Process Of Centella Asiatica By Acetobacter Tropicalis Inacc B374 Significantly Increases Thrombolytic Activity.
| Item Type: | Thesis (Skripsi) | |||||||||
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| Additional Information: | KKC KK FF.F.47-21 Nur p | |||||||||
| Uncontrolled Keywords: | Thrombolytic Activity, Acetobacter Tropicalis, Centella Asiatica, Clot Lysis, Fermentation. | |||||||||
| Subjects: | R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica |
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| Divisions: | 05. Fakultas Farmasi > S1 Farmasi | |||||||||
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| Depositing User: | Jadik jdkyanto Wijayanto | |||||||||
| Date Deposited: | 27 Oct 2021 02:44 | |||||||||
| Last Modified: | 24 Jun 2022 06:33 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/111703 | |||||||||
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