Debby Saputera, - and Intan Nirwana, - and Michael Josef Kridanto Kamadjaja, - (2021) Spectroscopy Structure Analysis of Ellagic Acid and Calcium Phosphate. Journal of International Dental and Medical Research, 14 (4). pp. 1435-1441. ISSN 1309-100X

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Abstract

Ellagic acid is a polyphenol found in pomegranates. It contains a stimulant of osteoblast genesis and anti-inflammatory properties, and it is osteo inductive. Bovine bone xenograft is also osteoconductive and becomes one of the properties of the bone graft matrix that supports the attachment of bone-forming cells. Fourier transform infrared (FTIR) is an instrument that uses spectroscopic principles. Infrared spectroscopy is useful for identifying organic compounds because of its very complex spectrum consisting of many peaks. This study determined the chemical bonds of ellagic acid, calcium phosphate, and their combination to the spectrum of functional groups produced. FTIR characterization was carried out with ellagic acid powder, bovine bone xenograft powder, and a combination of samples with a ratio of 50:50. The FTIR results from the combination of ellagic acid and calcium phosphate showed a shift in wavenumber. This research shows the combination of calcium phosphate and ellagic acid contain different functional groups. When combined, the compounds are still strong in ellagic acid.

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