Nur Rochmah, - and Muhammad Faizi, - and I. W. Triastuti, - and Garindra Wicaksono, - and Anang Endaryanto, - and Soetjipto, - (2022) Vitamin D level and early cow’s milk protein exposure in type 1 diabetes mellitus. ARCHIVES OF HELLENIC MEDICINE, 39 (1). pp. 106-109. ISSN 1105-3992

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Abstract

OBJECTIVE To analyze the association of vitamin D levels and cow’s milk exposure in children with type 1 diabetes mellitus (T1DM). METHOD This is a case control study of children with T1DM aged 4–18 years and healthy control subjects. The children were grouped by level of vitamin D according to the 2011 guidelines of the Task Force: deficiency (≤20 ng/mL), insufficiency (>20–30 ng/mL), and sufficiency (>30 ng/mL). The children’s history of cow’s milk exposure was obtained. Statistical analysis was performed using the independent t-test, Mann-Whitney test, and logistic regression, with significance set at p<0.05. RESULTS The study sample included 31 children with T1DM and 24 healthy control subjects. Vitamin D deficiency was detected in 4/31 children with T1DM, and none of the control subjects (p<0.001). Vitamin D deficiency and insufficiency were detected in 77.41% of the children with T1DM and 25% of the control subjects (p<0.001), and vitamin D deficiency and insufficiency were predictors of T1DM (odds ratio [OR]=3.09; p<0.001). The proportion of children exposed to cow’s milk in the first 3 months was 51.16% in the T1DM group and 50% in the control subjects (p=1.000). Logistic regression analysis showed that the vitamin D level was significantly corre- lated with T1DM (p=0.001). CONCLUSIONS Low vitamin D levels were shown to be correlated with T1DM, whereas early exposure to cow’s milk was not. Vitamin D supplementation is essential since it has an immunomodulatory effect. It is recommended to be given to T1DM children.

Item Type:	Article
Uncontrolled Keywords:	Children ; Cow’s milk ; Risk factors ; Type 1 diabetes mellitus Vitamin D
Subjects:	R Medicine > R Medicine (General) R Medicine > RJ Pediatrics
Divisions:	01. Fakultas Kedokteran > Ilmu Kesehatan Anak (Sub Spesialis)
Creators:	Creators NIM Nur Rochmah, - NIDN0029047909 Muhammad Faizi, - NIDN8890900016 I. W. Triastuti, - UNSPECIFIED Garindra Wicaksono, - UNSPECIFIED Anang Endaryanto, - NIDN8867700016 Soetjipto, - NIDN0017025004
Depositing User:	Mrs Elok Dian Nuraeni
Date Deposited:	30 May 2023 22:05
Last Modified:	30 May 2023 22:05
URI:	http://repository.unair.ac.id/id/eprint/126878
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• Vitamin D level and early cow’s milk protein exposure in type 1 diabetes mellitus. (deposited 09 May 2023 03:18)
  • Vitamin D level and early cow’s milk protein exposure in type 1 diabetes mellitus. (deposited 30 May 2023 22:05) [Currently Displayed]

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