Tri Martiana (1999) Pengaruh Perubahan Circadian Rhythm Terhadap Respons Imun Seluler Pada Pekerja Shilft Malam. Disertasi thesis, UNIVERSITAS AIRLANGGA.
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2. ABSTRACT.pdf Download (974kB) |
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Abstract
High upper respiratory tract infection incidence in factory using three shift rotating work schedulle indicates decreasing immune defense mechanism among workers, which resulting in adaptation failure ofthe workers to tircadiau rhythm during night shift work By employing quasi experimental research design and using similar working unit workers who never experiencing night shift work as a control, this study attempt to assess effect of circadian rhythm changes to immune defense mechanism during night shift Samples were selected among male workers, unmarried, 20 - 25 years old with good health status and no psychological disturbances. Respons Cortisol hormone was used as stress indicator, and cellular respons of monocyt, lymphocyt, neutrophyl, and NK cell were used as immune respons indicators. Data ware collected during 5 days working day This study ~est that cortisol hormone and neutrophyl cell play as an importance indicators in the circadian rhythm among workers. It was figurized in 4 different patterns according to inmnme respons , which also relate to coping mechanism . Two patterns appear in study group. The first is consider as adapted to circardian rliythm group which suggesting the development of coping strategy. The second group shows high respons of cortisol with low respons of neutrophyl cell caused by suppression of cortisol hormone. The latter consider as •madapted group. The study reveals that circadian rhythm changes can play a.S a stressors for rotating shift worker but can be adapted depends on adaptation ability. Unadapted workers show positive respons on neurohormonal which suppress cellular immtmity.
| Item Type: | Thesis (Disertasi) | |||||||||
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| Additional Information: | KKA KK DIS K 15-02 Mar p | |||||||||
| Uncontrolled Keywords: | circadian rhythm, night shift, coping mechanism, cortisol, immune | |||||||||
| Subjects: | R Medicine | |||||||||
| Divisions: | 01. Fakultas Kedokteran > S3 Ilmu Kedokteran | |||||||||
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| Depositing User: | Novita | |||||||||
| Date Deposited: | 02 Apr 2023 14:28 | |||||||||
| Last Modified: | 02 Apr 2023 14:28 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/121722 | |||||||||
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