Characteristic of bovine hydroxyapatite-gelatin-chitosan scaffolds as biomaterial candidate for bone tissue engineering

Nadia Kartikasari and Anita Yuliati and Indah Listiana Kriswandini and R. Darmawan Setijanto and Ketut Suardita and Maretaningtias Dwi Ariani and Agung Sosiawan (2016) Characteristic of bovine hydroxyapatite-gelatin-chitosan scaffolds as biomaterial candidate for bone tissue engineering. In: 2016 IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES). IEEE, Kuala Lumpur, pp. 623-626. ISBN 978-1-4673-7792-8

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Bone defect is still a major problem in dentistry. Solving this problem, tissue engineering becomes one of the promising methods for bone regeneration. One of main component of tissue engineering is scaffolds. Hydroxyapatite (HA) and natural polymer are widely used for scaffolds in bone tissue engineering due to similarity to the natural bone. In this study, the author prepared the scaffolds from bovine hydroxyapatite (BHA), gelatin (GEL) and chitosan (K). The prepared scaffolds were analyzed by using FTIR and SEM-EDX. In addition, its swelling and degradation rate are also included in this analysis. The results are (1) FTIR reveals the compositions of the scaffolds, and it consists of BHA, GEL, and K; (2) SEM-EDX reveals the elements of the scaffolds, and it consists of carbon (C), oxygen (O), natrium (Na), magnesium (Mg), phosphor (P), and calcium (Ca); (3) the scaffolds' swelling rate is good due to its hydrophilic composition; (4) and the degradation rate is low within three days. The four results show that the BHA-GEL-K scaffolds could be one of biomaterial candidate for bone tissue engineering.

Item Type: Book Section
Uncontrolled Keywords: Bones, Degradation, Calcium, Tissue engineering, Bone tissue, Bovine
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Dental Public Health
Nadia KartikasariNIM020710192
Anita YuliatiNIDN0009075803
Indah Listiana KriswandiniNIDN0030106303
R. Darmawan SetijantoNIDN0005106109
Ketut SuarditaNIDN0026116803
Maretaningtias Dwi ArianiNIDN0017038004
Agung SosiawanNIDN0011127110
Depositing User: Rudy Febiyanto
Date Deposited: 18 Sep 2019 02:01
Last Modified: 20 Apr 2023 08:37
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